Nancy Guthrie disappearance: Sheriff says no arrests, none remain in custody after major operation

A high-level source tells Fox News Digital that after last night’s activity in Tucson the FBI is still waiting for the Pima County Sheriff’s Department’s lab results.

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Pima County Sheriff Chris Nanos recently defended his department’s use of a private Florida lab, telling Fox News earlier this week that evidence was sent there early on and the FBI agreed it was best to continue to send evidence to the Florida lab, which the sheriff’s department has long contracted with, rather than to the FBI’s comprehensive crime lab in Quantico, Virginia.

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On Saturday morning, Nanos told Fox News that no arrests were made and no one was in custody in connection to the disappearance of Nancy Guthrie.

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Sources told Fox News Digital that a federal search warrant was executed Friday night at a Tucson home about two miles from Guthrie’s residence and at least three people were detained in connection to the operation.

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The sheriff’s department later confirmed the warrant was based on a “lead” law enforcement received.

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“Law enforcement activity is underway at a residence near E Orange Grove Rd & N First Ave related to the Guthrie case,” Pima County sheriff’s officials wrote in an X post. “Because this is a joint investigation, at the request of the FBI — no additional information is currently available.”

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A man was photographed in handcuffs at a nearby Culver’s parking lot. Sources told Fox News Digital that he was detained in connection to the search warrant, and he was seen being processed in the parking lot, but no charges were announced.

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Law enforcement also searched a Range Rover, which was towed from the lot.

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Authorities have not named any suspects or persons of interest.

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Fox News Digital’s Michael Ruiz and Alexandra Koch contributed to this report.